Dr Jaya Seneviratne
Senior Lecturer & Director of HDR (DHDR)
School of Dentistry
Affiliate of Centre for Orofacial Regeneration, Reconstruction and Rehabilitation (COR3)
Centre for Orofacial Regeneration, Reconstruction and Rehabilitation
Researcher biography
Dr. Jaya Seneviratne is a Senior Lecturer in Periodontology affiliated to the School of Dentistry, University of Queensland, Australia. Currently he serves as the Director of Higher Degree Research. Dr. Seneviratne is an internationally recognized academic and a researcher in the field of dentistry. His track record encompasses over 100 publications in renowned international journals, including all top journals in dental research, 12 book chapters and an edited book "Microbial Biofilms: OMICS Biology, Antimicrobials and Clinical Implications" Taylor & Francis CRC Press, 2017. He has successfully secured over US$ 7.11 million from competitive grants for his research and development work. Dr. Seneviratne served as the Secretary of the IADR-Asia Pacific Region (APR) from 2019-2022. He was also the Chairman of the Session Committee for the 2023 IADR General Meeting in Bogota, Colombia. Previously, he held the key positions as the Chairman of the IADR Constitution Committee and a member of the IADR Fellowship and Membership Committees. Currently, he is an Editorial board member of the Journal of Dental Research and Critical Reviews in Microbiology. Dr. Seneviratne has supervised both undergraduate and postgraduate students, mentoring them excel in their research work. His research mentees have received numerous prestigious awards from the IADR. His primary research interests include oral microbiome, oral biofilms, oral-systemic link and infection control.
Book Chapters
Seneviratne, Chaminda Jayampath, Srivastava, Neha, Islam, Intekhab, Foong, Kelvin and Allen, Finbarr (2017). Microbial biofilms: an introduction to their development, properties and clinical implications. Microbial biofilms: omics biology, antimicrobials and clinical implications. (pp. 1-31) edited by Chaminda Jayampath Seneviratne. Boca Raton, FL, United States: CRC Press. doi: 10.4324/9781315120119-1
Venkiteswaran, Nityasri, Ellepola, Kassapa, Seneviratne, Chaminda Jayampath, Lee, Yuan Kun, Puan, Kia Joo and Wong, Siew Cheng (2017). Host-Biofilm Interactions at Mucosal Surfaces and Implications in Human Health. Microbial Biofilms: Omics Biology, Antimicrobials and Clinical Implications. (pp. 203-235) Boca Raton, FL United States: CRC Press. doi: 10.4324/9781315120119-9
Li, Peng, Seneviratne, Chaminda Jayampath and Jin, Lijian (2017). Biofilm Persisters Formation, Molecular Mechanisms and Strategies for Tackling. Microbial Biofilms: Omics Biology, Antimicrobials and Clinical Implications. (pp. 193-202) Boca Raton, FL United States: CRC Press. doi: 10.4324/9781315120119-8
Seneviratne, Chaminda Jayampath and Jayasinghe, Ruwan Duminda (2015). Association of candida with linear gingival erythema in HIV-infected subjects. Oral Candidosis: Physiopathology, Decision Making, and Therapeutics. (pp. 83-94) Springer Berlin Heidelberg. doi: 10.1007/978-3-662-47194-4_12
Seneviratne, C. J. and Samaranayake, L. P. (2011). An overview of H5N1 infection and its implications for dentistry. Clinical Dentistry. (pp. 9-28) Nova Science Publishers, Inc..
Seneviratne, C. Jayampath and Samaranayake, Lakshman P. (2011). Drug resistance mechanisms of fungal biofilms. Biofilms: Formation, Development and Properties. (pp. 373-396) Nova Science Publishers, Inc..
Journal Articles
Chee, Hoe Kit, Abbas, Frank, van Winkelhoff, Arie Jan, Tjakkes, Geerten Has, Htoon, Hla Myint, Li, Huihua, de Waal, Yvonne, Vissink, Arjan and Seneviratne, Chaminda Jayampath (2024). Identifying Undiagnosed Diabetes and Prediabetes in the Dental Setting in an Asian Population—A Clinical Risk Model. Journal of Clinical Periodontology. doi: 10.1111/jcpe.14090
Sari Widyarman, Armelia, Udawatte, Nadeeka S., Tegar Badruzzaman, Idham, Cloudya Panjaitan, Caesary, Apriani, Anie, Jeddy,, Erri Astoeti, Tri and Jayampath Seneviratne, Chaminda (2024). Topical fluoride varnish application shifts dysbiotic dental plaque microbiome towards eubiosis in children with dental caries. The Saudi Dental Journal, 36 (10), 1313-1320. doi: 10.1016/j.sdentj.2024.07.010
Li, Hongze, Yang, Zhihe, Khan, Sadaf Aiman, Walsh, Laurence J., Seneviratne, Chaminda Jayampath and Ziora, Zyta M. (2024). Characteristics of metallic nanoparticles (especially silver nanoparticles) as anti-biofilm agents. Antibiotics, 13 (9) 819. doi: 10.3390/antibiotics13090819
Wang, Cong, Xu, Tian, Seneviratne, Chaminda Jayampath, Ong, Louis Jun Ye and Zhou, Yinghong (2024). Modelling periodontitis in vitro: engineering strategies and biofilm model development. Frontiers in Biomaterials Science, 3 1380153. doi: 10.3389/fbiom.2024.1380153
Khan, Sadaf Aiman, Zeng, Junya, Jain, Marut, Pant, Kamal Kishore, Ziora, Zyta Maria, Blaskovich, Mark A.T. and Seneviratne, Chaminda Jayampath (2024). Facile one-pot fabrication of multifunctional silver nanoparticles utilizing biowaste for efficient pollutant degradation, heavy metal sensing, and bactericidal activity. Materials Chemistry and Physics, 322 129606, 129606. doi: 10.1016/j.matchemphys.2024.129606
Wijesekera, Akila, Weeramange, Chameera Ekanayake, Vasani, Sarju, Kenny, Liz, Knowland, Emma, Seneviratne, Jayampath and Punyadeera, Chamindie (2024). Surveillance of human papillomavirus through salivary diagnostics - A roadmap to early detection of oropharyngeal cancer men. Tumour Virus Research, 17 200278. doi: 10.1016/j.tvr.2024.200278
Liu, Chun, Yazdani, Negar, Moran, Corey S., Salomon, Carlos, Seneviratne, Chaminda Jayampath, Ivanovski, Sašo and Han, Pingping (2024). Unveiling clinical applications of bacterial extracellular vesicles as natural nanomaterials in disease diagnosis and therapeutics. Acta Biomaterialia, 180, 18-45. doi: 10.1016/j.actbio.2024.04.022
Belibasakis, Georgios N., Senevirantne, Chaminda Jayampath, Jayasinghe, Ruwan Duminda, Vo, Phuc Thi-Duy, Bostanci, Nagihan and Choi, Youngnim (2024). Bacteriome and mycobiome dysbiosis in oral mucosal dysplasia and oral cancer. Periodontology 2000, 96 (1), 95-111. doi: 10.1111/prd.12558
Ng, Ethan, Tay, John Rong Hao, Mattheos, Nikos, Bostanci, Nagihan, Belibasakis, Georgios N. and Seneviratne, Chaminda Jayampath (2024). A Mapping Review of the Pathogenesis of Peri-Implantitis: The Biofilm-Mediated Inflammation and Bone Dysregulation (BIND) Hypothesis. Cells, 13 (4) 315, 315. doi: 10.3390/cells13040315
Ng, Ethan, Tay, John Rong Hao, Boey, Sean Kuan, Laine, Marja L, Ivanovski, Sašo and Seneviratne, Chaminda Jayampath (2024). Antibiotic resistance in the microbiota of periodontitis patients: an update of current findings. Critical Reviews in Microbiology, 50 (3), 329-340. doi: 10.1080/1040841x.2023.2197481
Suriyanarayanan, Tanujaa, Lee, Lye Siang, Han, Sharon Hong Yu, Ching, Jianhong and Seneviratne, Chaminda J. (2024). Targeted metabolomics analysis approach to unravel the biofilm formation pathways of Enterococcus faecalis clinical isolates. International Endodontic Journal, 57 (10), 1505-1520. doi: 10.1111/iej.14110
Liu, Chun, Seneviratne, Chaminda Jayampath, Palma, Carlos, Rice, Greg, Salomon, Carlos, Khanabdali, Ramin, Ivanovski, Sašo and Han, Pingping (2023). Immunoaffinity-enriched salivary small extracellular vesicles in periodontitis. Extracellular Vesicles and Circulating Nucleic Acids, 4 (4), 698-712. doi: 10.20517/evcna.2023.48
Almuqrin, Amjad, Kaur, Inder Preet, Walsh, Laurence J., Seneviratne, Chaminda Jayampath and Zafar, Sobia (2023). Amelioration strategies for silver diamine fluoride: moving from black to white. Antibiotics, 12 (2) 298, 1-18. doi: 10.3390/antibiotics12020298
Balan, Preethi, Belibasakis, Georgios, Ivanovski, Saso, Bostanci, Nagihan and Seneviratne, Chaminda Jayampath (2023). Community dynamics of subgingival microbiome in periodontitis and targets for microbiome modulation therapy. Critical Reviews in Microbiology, 49 (6), 726-738. doi: 10.1080/1040841X.2022.2133594
Agarwalla, Shruti Vidhawan, Ellepola, Kassapa, Sorokin, Vitaly, Ihsan, Mario, Silikas, Nikolaos, Neto, AH Castro, Seneviratne, Chaminda Jayampath and Rosa, Vinicius (2022). Antimicrobial-free graphene nanocoating decreases fungal yeast-to-hyphal switching and maturation of cross-kingdom biofilms containing clinical and antibiotic-resistant bacteria. Biomaterials and Biosystems, 8 100069, 1-7. doi: 10.1016/j.bbiosy.2022.100069
Theodorea, Citra Fragrantia, Diven, Saint, Hendrawan, Devin, Djais, Ariadna Adisattya, Bachtiar, Boy Muchlis, Widyarman, Armelia Sari and Seneviratne, Chaminda Jayampath (2022). Characterization of oral veillonella species in dental biofilms in healthy and stunted groups of children aged 6–7 years in East Nusa Tenggara. International Journal of Environmental Research and Public Health, 19 (21) 13998, 1-9. doi: 10.3390/ijerph192113998
Samaranayake, Lakshman Perera, Seneviratne, Chaminda Jayampath and Fakhruddin, Kausar Sadia (2022). Coronavirus disease 2019 (COVID-19) vaccines: a concise review. Oral Diseases, 28 (S2), 2326-2336. doi: 10.1111/odi.13916
Seneviratne, Chaminda Jayampath, Balan, Preethi, de Alwis, Ruklanthi, Udawatte, Nadeeka S., Herath, Thanuja, Toh, Justin Z. N., Tin, Goh Bee, Ooi, Eng Eong, Hong, Jenny Low Guek and Ying, Jean Sim Xiang (2022). BNT162b2 mRNA vaccine–induced immune response in oral fluids and serum. International Dental Journal, 73 (3), 435-442. doi: 10.1016/j.identj.2022.09.005
Widyarman, Armelia Sari, Udawatte, Nadeeka S., Roeslan, Moehamad Orliando, Rizal, Muhammad Ihsan, Richi, Mario, Kusnoto, Joko and Seneviratne, Chaminda Jayampath (2022). Short- term effect of probiotic Lactobacillus reuteri consumption on the salivary microbiome profile of subjects undergoing orthodontic treatment with fixed appliances. Journal of Oral Microbiology, 14 (1) 2067103, 1-11. doi: 10.1080/20002297.2022.2067103
Ng, E., Tay, J. R.H., Leung, N. H.L. and Seneviratne, C. J. (2022). Letter to the Editor, “Sources of SARS-CoV-2 and Other Microorganisms in Dental Aerosols”. Journal of Dental Research, 101 (2), 236-236. doi: 10.1177/00220345211037224
Balan, Preethi, Chong, Yap Seng, Lin, Qingsong, Lim, Teck Kwang, Suriyanarayanan, Tanujaa, Udawatte, Nadeeka Shiyamalee, Wong, Mun Loke, Lopez, Violeta, He, Hong-Gu and Seneviratne, Chaminda Jayampath (2022). Salivary proteomic profiling identifies role of neutrophil extracellular traps formation in pregnancy gingivitis. Immunological Investigations, 51 (1), 103-119. doi: 10.1080/08820139.2020.1810704
Herath, Thanuja D. K., Darveau, Richard P., Seneviratne, Chaminda J., Wang, Cun-Yu, Wang, Yu and Jin, Lijian (2021). Author Correction: Heterogeneous Porphyromonas gingivalis LPS modulates immuno-inflammatory response, antioxidant defense and cytoskeletal dynamics in human gingival fibroblasts (Scientific Reports, (2016), 6, 1, (29829), 10.1038/srep29829). Scientific Reports, 11 (1) 2337. doi: 10.1038/s41598-021-81798-0
Balan, Preethi, Chong, Yap S., Lin, Qingsong, Lim, Teck Kwang, Li, Huihua, Wong, Mun L., Lopez, Violeta, He, Hong Gu and Seneviratne, Chaminda Jayampath (2021). Isobaric tags for relative and absolute quantification (iTRAQ)-based quantitative analysis of the salivary proteome during healthy pregnancy and pregnancy gingivitis. Journal of Clinical Periodontology, 48 (12), 1559-1569. doi: 10.1111/jcpe.13559
Da Jason, Chua Sheng, Seneviratne, Chaminda Jayampath, Wong, Hung Chew and Yow, Mimi (2021). Effects of Hawley, Essix, and Vivera® retainers on salivary properties, oral hygiene, and Streptococcus mutans levels: a prospective clinical pilot study. APOS Trends in Orthodontics, 11 (3) 198, 198-208. doi: 10.25259/APOS_5_2021
Rosa, V., Malhotra, R., Agarwalla, S. V., Morin, J. L.P., Luong-Van, E. K., Han, Y. M., Chew, R. J.J., Seneviratne, C. J., Silikas, N., Tan, K. S., Nijhuis, C. A. and Castro Neto, A. H. (2021). Graphene nanocoating: high quality and stability upon several stressors. Journal of Dental Research, 100 (10), 1169-1177. doi: 10.1177/00220345211024526
Balan, P., Brandt, B. W., Chong, Y. S., Crielaard, W., Wong, M. L., Lopez, V., He, H. G. and Seneviratne, C. J. (2021). Subgingival microbiota during healthy pregnancy and pregnancy gingivitis. JDR Clinical and Translational Research, 6 (3), 343-351. doi: 10.1177/2380084420948779
Balan, Preethi, Chong, Yap Seng, Qingsong, Lin, Lim, Teck Kwang, Wong, Mun Loke, Lopez, Violeta, Hong-Gu, H. E. and Seneviratne, Chaminda Jayampath (2021). Quantitative proteomics analysis identifies salivary biomarkers for early detection of pregnancy loss in a Singaporean cohort—a pilot study. Proteomics - Clinical Applications, 15 (4) 2000068. doi: 10.1002/prca.202000068
Ng, Ethan, Tay, John R. H., Balan, P., Ong, Marianne M. A., Bostanci, Nagihan, Belibasakis, Georgios N. and Seneviratne, Chaminda J. (2021). Metagenomic sequencing provides new insights into the subgingival bacteriome and aetiopathology of periodontitis. Journal of Periodontal Research, 56 (2), 205-218. doi: 10.1111/jre.12811
Seneviratne, Chaminda J., Balan, Preethi, Ko, Kwan Ki Karrie, Udawatte, Nadeeka S., Lai, Deborah, Ng, Dorothy Hui Lin, Venkatachalam, Indumathi, Lim, Kheng Sit, Ling, Moi Lin, Oon, Lynette, Goh, Bee Tin and Sim, Xiang Ying Jean (2021). Efficacy of commercial mouth-rinses on SARS-CoV-2 viral load in saliva: randomized control trial in Singapore. Infection, 49 (2), 305-311. doi: 10.1007/s15010-020-01563-9
Chen, Yong, Wong, Wing Kit, Seneviratne, Jayampath C., Huang, Shuying, McGrath, Colman and Hagg, Urban (2021). Associations between salivary cytokines and periodontal and microbiological parameters in orthodontic patients. Medicine (United States), 100 (10) e24924, 1-7. doi: 10.1097/MD.0000000000024924
Widyarman, Armelia Sari, Udawatte, Nadeeka S., Theodorea, Citra Fragrantia, Apriani, Anie, Richi, Mario, Astoeti, Tri Erri and Seneviratne, Chaminda Jayampath (2021). Casein phosphopeptide–amorphous calcium phosphate fluoride treatment enriches the symbiotic dental plaque microbiome in children. Journal of Dentistry, 106 103582, 1-8. doi: 10.1016/j.jdent.2021.103582
Li, Peng, Seneviratne, Chaminda J., Luan, Qingxian and Jin, Lijian (2021). Proteomic analysis of Caspofungin-induced responses in planktonic cells and biofilms of Candida albicans. Frontiers in Microbiology, 12 639123, 1-11. doi: 10.3389/fmicb.2021.639123
Agarwalla, Shruti Vidhawan, Ellepola, Kassapa, Silikas, Nikolaos, Castro Neto, A. H., Seneviratne, Chaminda Jayampath and Rosa, Vinicius (2021). Persistent inhibition of Candida albicans biofilm and hyphae growth on titanium by graphene nanocoating. Dental Materials, 37 (2), 370-377. doi: 10.1016/j.dental.2020.11.028
Foo, Lean Heong, Balan, Preethi, Pang, Li Mei, Laine, Marja L. and Seneviratne, Chaminda Jayampath (2021). Role of the oral microbiome, metabolic pathways, and novel diagnostic tools in intra-oral halitosis: a comprehensive update. Critical Reviews in Microbiology, 47 (3), 359-375. doi: 10.1080/1040841X.2021.1888867
Ng, E., Tay, J. R. H., Ong, M. M. A., Bostanci, N., Belibasakis, G. N. and Seneviratne, C. J. (2021). Probiotic therapy for periodontal and peri-implant health – silver bullet or sham?. Beneficial Microbes, 12 (3), 215-230. doi: 10.3920/BM2020.0182
Tay, John Rong Hao, Ng, Ethan, Ong, Marianne Meng Ann, Sim, Chelsia, Tan, Ken and Seneviratne, Chaminda Jayampath (2020). A risk-based approach to the COVID-19 pandemic: the experience in National Dental Centre Singapore. Frontiers in Medicine, 7 562728, 1-10. doi: 10.3389/fmed.2020.562728
Seneviratne, Chaminda J., Suriyanarayanan, Tanujaa, Widyarman, Armelia Sari, Lee, Lye Siang, Lau, Matthew, Ching, Jianhong, Delaney, Christopher and Ramage, Gordon (2020). Multi-omics tools for studying microbial biofilms: current perspectives and future directions. Critical Reviews in Microbiology, 46 (6), 759-778. doi: 10.1080/1040841X.2020.1828817
Chan, Ally, Ellepola, Kassapa, Truong, Thuyen, Balan, Preethi, Koo, Hyun and Seneviratne, Chaminda Jayampath (2020). Inhibitory effects of xylitol and sorbitol on Streptococcus mutans and Candida albicans biofilms are repressed by the presence of sucrose. Archives of Oral Biology, 119 104886, 1-12. doi: 10.1016/j.archoralbio.2020.104886
Seneviratne, Chaminda Jayampath, Lau, Matthew Wen Jian and Goh, Bee Tin (2020). The role of dentists in COVID-19 is beyond dentistry: voluntary medical engagements and future preparedness. Frontiers in Medicine, 7 566, 1-7. doi: 10.3389/fmed.2020.00566
Truong, Thuyen, Pang, Li Mei, Rajan, Suhasini, Wong, Sarah Sze Wah, Fung, Yi Man Eva, Samaranayake, Lakshman and Seneviratne, Chaminda Jayampath (2020). The proteome of community living Candida albicans is differentially modulated by the morphologic and structural features of the bacterial cohabitants. Microorganisms, 8 (10) 1541, 1-15. doi: 10.3390/microorganisms8101541
Srivastava, Neha, Ellepola, Kassapa, Venkiteswaran, Nityasri, Chai, Louis Yi Ann, Ohshima, Tomoko and Seneviratne, Chaminda Jayampath (2020). Lactobacillus plantarum 108 inhibits Streptococcus mutans and Candida albicans mixed‐species biofilm formation. Antibiotics, 9 (8) 478, 1-20. doi: 10.3390/antibiotics9080478
Seneviratne, Chaminda Jayampath, Balan, Preethi, Suriyanarayanan, Tanujaa, Lakshmanan, Meiyappan, Lee, Dong-Yup, Rho, Mina, Jakubovics, Nicholas, Brandt, Bernd, Crielaard, Wim and Zaura, Egija (2020). Oral microbiome-systemic link studies: perspectives on current limitations and future artificial intelligence-based approaches. Critical Reviews in Microbiology, 46 (3), 288-299. doi: 10.1080/1040841X.2020.1766414
Udawatte, Nadeeka S., Kang, Sung Wook, Wang, Yue, Arumugam, Thiruma V. and Seneviratne, Chaminda J. (2020). Predictive nephrotoxicity profiling of a novel antifungal small molecule in comparison to amphotericin B and voriconazole. Frontiers in Pharmacology, 11 511. doi: 10.3389/fphar.2020.00511
Truong, Thuyen, Zeng, Guisheng, Lim, Teck Kwang, Cao, Tong, Pang, Li Mei, Lee, Yew Mun, Lin, Qingsong, Wang, Yue and Seneviratne, Chaminda Jayampath (2020). Proteomics analysis of Candida albicans dnm1 haploid mutant unraveled the association between mitochondrial fission and antifungal susceptibility. Proteomics, 20 (1) 1900240, 1-12. doi: 10.1002/pmic.201900240
Patil, Shankargouda, Habib Awan, Kamran, Arakeri, Gururaj, Jayampath Seneviratne, Chaminda, Muddur, Nagaraj, Malik, Shuaib, Ferrari, Marco, Rahimi, Siavash and Brennan, Peter A. (2019). Machine learning and its potential applications to the genomic study of head and neck cancer—a systematic review. Journal of Oral Pathology and Medicine, 48 (9), 773-779. doi: 10.1111/jop.12854
Ellepola, K., Truong, T., Liu, Y., Lin, Q., Lim, T. K., Lee, Y. M., Cao, T., Koo, H. and Seneviratne, C. J. (2019). Multi-omics analyses reveal synergistic carbohydrate metabolism in Streptococcus mutans-Candida albicans mixed-species biofilms. Infection and Immunity, 87 (10) e00339-19, 1-20. doi: 10.1128/IAI.00339-19
Agarwalla, Shruti Vidhawan, Ellepola, Kassapa, Costa, Mariana Caldeira Ferraz da, Fechine, Guilhermino José Macêdo, Morin, Julien Luc Paul, Castro Neto, A. H., Seneviratne, Chaminda Jayampath and Rosa, Vinicius (2019). Hydrophobicity of graphene as a driving force for inhibiting biofilm formation of pathogenic bacteria and fungi. Dental Materials, 35 (3), 403-413. doi: 10.1016/j.dental.2018.09.016
Li, Hua Jing, Seneviratne, Chaminda Jayampath, Wang, Cun Yu and Jin, Li Jian (2019). Periodontal commensals and pathogens differentially modulate immuno-inflammatory response in human oral keratinocytes. The Chinese Journal of Dental Research, 22 (2), 105-112. doi: 10.3290/j.cjdr.a42514
Balan, Preethi, Chong, Yap Seng, Umashankar, Shivshankar, Swarup, Sanjay, Loke, Wong Mun, Lopez, Violeta, He, Hong Gu and Seneviratne, Chaminda Jayampath (2018). Keystone species in pregnancy gingivitis: a snapshot of oral microbiome during pregnancy and postpartum period. Frontiers in Microbiology, 9 (OCT) 2360, 1-11. doi: 10.3389/fmicb.2018.02360
Suriyanarayanan, Tanujaa, Qingsong, Lin, Kwang, Lim Teck, Mun, Lee Yew, Truong, Thuyen and Seneviratne, Chaminda Jayampath (2018). Correction: Quantitative proteomics of strong and weak biofilm formers of Enterococcus faecalis reveals novel regulators of biofilm formation (Molecular and Cellular Proteomics (2018) 17 (643-654) DOI: 10.1074/mcp.RA117.000461). Molecular and Cellular Proteomics, 17 (10). doi: 10.1074/mcp.AAC118.001077
Li, Peng, Fung, Yi-Man Eva, Yin, Xiaohui, Seneviratne, Chaminda J., Che, Chi-Ming and Jin, Lijian (2018). Controlled cellular redox, repressive hemin utilization and adaptive stress responses are crucial to metronidazole tolerance of Porphyromonas gingivalis persisters. Journal of Clinical Periodontology, 45 (10), 1211-1221. doi: 10.1111/jcpe.13002
Balan, Preethi, He, Hong-Gu, Cao, Fengchunzhi, Wong, Mun Loke, Chong, Yap-Seng, Lopez, Violeta, Soh, Shu-E. and Seneviratne, Chaminda Jayampath (2018). Oral health in pregnant Chinese women in Singapore: a call to go beyond the traditional clinical care. Healthcare, 6 (3) 77, 1-12. doi: 10.3390/healthcare6030077
Sam, Qi Hui, Yew, Wen Shan, Seneviratne, Chaminda J., Chang, Matthew Wook and Chai, Louis Yi Ann (2018). Immunomodulation as therapy for fungal infection: are we closer?. Frontiers in Microbiology, 9 (JUL) 1612, 1-16. doi: 10.3389/fmicb.2018.01612
Truong, Thuyen, Suriyanarayanan, Tanujaa, Zeng, Guisheng, Le, Thuc D., Liu, Lin, Li, Jiuyong, Tong, Cao, Wang, Yue and Seneviratne, Chaminda J. (2018). Use of haploid model of Candida albicans to uncover mechanism of action of a novel antifungal agent. Frontiers in Cellular and Infection Microbiology, 8 164. doi: 10.3389/fcimb.2018.00164
Pereira, D. F. A., Seneviratne, C. J., Koga-Ito, C. Y. and Samaranayake, L. P. (2018). Is the oral fungal pathogen Candida albicans a cariogen?. Oral Diseases, 24 (4), 518-526. doi: 10.1111/odi.12691
Suriyanarayanan, Tanujaa, Qingsong, Lin, Kwang, Lim Teck, Mun, Lee Yew and Seneviratne, Chaminda Jayampath (2018). Quantitative proteomics of strong and weak biofilm formers of Enterococcus faecalis reveals novel regulators of biofilm formation. Molecular and Cellular Proteomics, 17 (4), 643-654. doi: 10.1074/mcp.RA117.000461
Dubey, Nileshkumar, Ellepola, Kassapa, Decroix, Fanny E. D., Morin, Julien L. P., Castro Neto, A. H., Seneviratne, Chaminda J. and Rosa, Vinicius (2018). Graphene onto medical grade titanium: an atom-thick multimodal coating that promotes osteoblast maturation and inhibits biofilm formation from distinct species. Nanotoxicology, 12 (4), 274-289. doi: 10.1080/17435390.2018.1434911
Zhu, Qian, Li, Mingming, Yan, Chuan, Lu, Qiqi, Wei, Shunhui, Gao, Rong, Yu, Mengfei, Zou, Yu, Sriram, Gopu, Tong, Huei J., Hunziker, Walter, Seneviratne, Chaminda J., Gong, Zhiyuan, Olsen, Bjorn R. and Cao, Tong (2017). Directed differentiation of human embryonic stem cells to neural crest stem cells, functional peripheral neurons, and corneal keratocytes. Biotechnology Journal, 12 (12) 1700067, 1-11. doi: 10.1002/biot.201700067
Ellepola, K., Liu, Y., Cao, T., Koo, H. and Seneviratne, C. J. (2017). Bacterial GtfB augments Candida albicans accumulation in cross-kingdom biofilms. Journal of Dental Research, 96 (10), 1129-1135. doi: 10.1177/0022034517714414
Seneviratne, Chaminda J., Suriyanarayanan, Tanujaa, Swarup, Sanjay, Chia, Kuan Hui Burton, Nagarajan, Niranjan and Zhang, Chengfei (2017). Transcriptomics analysis reveals putative genes involved in biofilm formation and biofilm-associated drug resistance of Enterococcus faecalis. Journal of Endodontics, 43 (6), 949-955. doi: 10.1016/j.joen.2017.01.020
Ho, Cindy S.F., Ming, Yue, Foong, Kelvin W.C., Rosa, Vinicius, Thuyen, Truong and Seneviratne, Chaminda J. (2017). Streptococcus mutans forms xylitol-resistant biofilm on excess adhesive flash in novel ex-vivo orthodontic bracket model. American Journal of Orthodontics and Dentofacial Orthopedics, 151 (4), 669-677. doi: 10.1016/j.ajodo.2016.09.017
Truong, Thuyen, Zeng, Guisheng, Lin, Qingsong, Kwang, Lim Teck, Tong, Cao, Chan, Fong Yee, Wang, Yue and Seneviratne, Chaminda Jayampath (2016). Comparative ploidy proteomics of Candida albicans biofilms unraveled the role of the AHP1 gene in the biofilm persistence against amphotericin B. Molecular and Cellular Proteomics, 15 (11), 3488-3500. doi: 10.1074/mcp.M116.061523
Sriram, Gopu, Natu, Vaishali Prakash, Islam, Intekhab, Fu, Xin, Seneviratne, Chaminda Jayampath, Tan, Kai Soo and Cao, Tong (2016). Innate immune response of human embryonic stem cell-derived fibroblasts and mesenchymal stem cells to periodontopathogens. Stem Cells International, 2016 (1) 8905365, 1-15. doi: 10.1155/2016/8905365
Herath, Thanuja D. K., Darveau, Richard P., Seneviratne, Chaminda J., Wang, Cun-Yu, Wang, Yu and Jin, Lijian (2016). Heterogeneous Porphyromonas gingivalis LPS modulates immuno-inflammatory response, antioxidant defense and cytoskeletal dynamics in human gingival fibroblasts. Scientific Reports, 6 29829. doi: 10.1038/srep29829
Leung, Ken Cham-Fai, Seneviratne, Chaminda Jayampath, Li, Xuan, Leung, Ping Chung, Lau, Clara Bik San, Wong, Chi-Hin, Pang, Ka Yan, Wong, Chun Wai, Wat, Elaine and Jin, Lijian (2016). Synergistic antibacterial effects of nanoparticles encapsulated with Scutellaria baicalensis and pure chlorhexidine on oral bacterial biofilms. Nanomaterials, 6 (4) 61, 1-11. doi: 10.3390/nano6040061
Seneviratne, Chaminda J., Rajan, Suhasini, Wong, Sarah S. W., Tsang, Dominic N. C., Lai, Christopher K. C., Samaranayake, Lakshman P. and Jin, Lijian (2016). Antifungal susceptibility in serum and virulence determinants of Candida bloodstream isolates from Hong Kong. Frontiers in Microbiology, 7 (FEB) 216, 1-8. doi: 10.3389/fmicb.2016.00216
Kojima, Yukako, Ohshima, Tomoko, Seneviratne, Chaminda Jayampath and Maeda, Nobuko (2016). Combining prebiotics and probiotics to develop novel synbiotics that suppress oral pathogens. Journal of Oral Biosciences, 58 (1), 27-32. doi: 10.1016/j.job.2015.08.004
Seneviratne, Chaminda J. and Rosa, Edvaldo A.R. (2016). Editorial: Antifungal drug discovery: New theories and new therapies. Frontiers in Microbiology, 7 (MAY) 728. doi: 10.3389/fmicb.2016.00728
Ohshima, Tomoko, Kojima, Yukako, Seneviratne, Chaminda J. and Maeda, Nobuko (2016). Therapeutic application of synbiotics, a fusion of probiotics and prebiotics, and biogenics as a new concept for oral Candida infections: A mini review. Frontiers in Microbiology, 7 (JAN) 00010. doi: 10.3389/fmicb.2016.00010
Wang, Shuai, Deng, Zuhui, Seneviratne, Chaminda J, Cheung, Gary Sp, Jin, Lijian, Zhao, Baohong and Zhang, Chengfei (2015). Enterococcus faecalis promotes osteoclastogenesis and semaphorin 4D expression. Innate Immunity, 21 (7), 726-735. doi: 10.1177/1753425915593162
Li, Peng, Seneviratne, Chaminda J., Alpi, Emanuele, Vizcaino, Juan A. and Jin, Lijian (2015). Delicate metabolic control and coordinated stress response critically determine antifungal tolerance of Candida albicans biofilm persisters. Antimicrobial Agents and Chemotherapy, 59 (10), 6101-6112. doi: 10.1128/AAC.00543-15
Li, Chun Lei, Seneviratne, Chaminda Jayampath, Huo, Lei, Lu, Weijia William and Zheng, Li Wu (2015). Impact of Actinomyces naeslundii on bisphosphonate-related osteonecrosis of the jaws in ovariectomized rats with periodontitis. Journal of Cranio-Maxillofacial Surgery, 43 (8), 1662-1669. doi: 10.1016/j.jcms.2015.07.001
Seneviratne, Chaminda Jayampath, Zeng, Guisheng, Truong, Thuyen, Sze, Sarah, Wong, Wah, Samaranayake, Lakshman, Chan, Fong Yee, Wang, Yan-Ming, Wang, Haitao, Gao, Jiaxin and Wang, Yue (2015). New "haploid biofilm model" unravels IRA2 as a novel regulator of Candida albicans biofilm formation. Scientific Reports, 5 (1) 12433, 12433.1-12433.12. doi: 10.1038/srep12433
Seneviratne, Chaminda Jayampath, Fong, Phoenix, Wong, Sarah and Lee, Victor (2015). Antifungal susceptibility and phenotypic characterization of oral isolates of a black fungus from a nasopharyngeal carcinoma patient under radiotherapy. BMC Oral Health, 15 (1) 39. doi: 10.1186/s12903-015-0023-9
Villard, Nicolas, Seneviratne, Chaminda, Tsoi, James Kit Hon, Heinonen, Markku and Matinlinna, Jukka (2015). Candida albicans aspects of novel silane system-coated titanium and zirconia implant surfaces. Clinical Oral Implants Research, 26 (3), 332-341. doi: 10.1111/clr.12338
Teodoro, Guilherme R., Ellepola, Kassapa, Seneviratne, Chaminda J. and Koga-Ito, Cristiane Y. (2015). Potential use of phenolic acids as anti-Candida agents: A review. Frontiers in Microbiology, 6 (DEC) 01420. doi: 10.3389/fmicb.2015.01420
Seneviratne, Chaminda Jayampath, Leung, Ken Cham-Fai, Wong, Chi-Hin, Lee, Siu-Fung, Li, Xuan, Leung, Ping Chung, Lau, Clara Bik San, Wat, Elaine and Jin, Lijian (2014). Nanoparticle-encapsulated chlorhexidine against oral bacterial biofilms. PLoS ONE, 9 (8) e103234, e103234. doi: 10.1371/journal.pone.0103234
Wong, Sarah S. W., Samaranayake, Lakshman P. and Senevirate, Chaminda J. (2014). In pursuit of the ideal antifungal agent for Candida infections: high-throughput screening of small molecules. Drug Discovery Today, 19 (11), 1721-1730. doi: 10.1016/j.drudis.2014.06.009
Wong, Sarah Sze Wah, Kao, Richard Yi Tsun, Yuen, Kwok Yong, Wang, Yu, Yang, Dan, Samaranayake, Lakshman Perera and Seneviratne, Chaminda Jayampath (2014). In vitro and in vivo activity of a novel antifungal small molecule against Candida infections. PLoS ONE, 9 (1) e85836, 1-17. doi: 10.1371/journal.pone.0085836
Wang, Shuai, Guo, Lihong, Seneviratne, Chaminda Jayampath, Huang, Bo, Han, Jianmin, Peng, Lei, Liu, Xiaodi and Zhang, Chengfei (2014). Biofilm formation of salivary microbiota on dental restorative materials analyzed by denaturing gradient gel electrophoresis and sequencing. Dental Materials Journal, 33 (3), 325-331. doi: 10.4012/dmj.2013-152
Tan, Chow-Ming, Tsoi, James Kit-Hon, Seneviratne, Chaminda Jayampath and Matinlinna, Jukka Pekka (2014). Evaluation of the Candida albicans removal and mechanical properties of denture acrylics cleaned by a low-cost powered toothbrush. Journal of Prosthodontic Research, 58 (4), 243-251. doi: 10.1016/j.jpor.2014.06.002
Chen, Yong, Wong, Ricky W.K., McGrath, Colman, Hagg, Urban and Seneviratne, C. Jayampath (2014). Natural compounds containing mouthrinses in the management of dental plaque and gingivitis: A systematic review. Clinical Oral Investigations, 18 (1), 1-16. doi: 10.1007/s00784-013-1033-0
Chen Y., Wong R.W.K., Seneviratne C.J., Hagg U., Mcgrath C. and Samaranayake L.P. (2013). The effects of natural compounds-containing mouthrinses on patients with fixed orthodontic appliance treatment: Clinical and microbiological outcomes. International Journal of Paediatric Dentistry, 23 (6), 452-459. doi: 10.1111/ipd.12018
Seneviratne, C.J., Yip, J.W.Y., Chang, J.W.W., Zhang, C.F. and Samaranayake, L.P. (2013). Effect of culture media and nutrients on biofilm growth kinetics of laboratory and clinical strains of Enterococcus faecalis. Archives of Oral Biology, 58 (10), 1327-1334. doi: 10.1016/j.archoralbio.2013.06.017
Herath, Thanuja D. K., Wang, Yu, Seneviratne, Chaminda J, Darveau, Richard P, Wang, Cun-Yu and Jin, Lijian (2013). The expression and regulation of matrix metalloproteinase-3 is critically modulated by Porphyromonas gingivalis lipopolysaccharide with heterogeneous lipid A structures in human gingival fibroblasts. BMC Microbiology, 13 (1) 73. doi: 10.1186/1471-2180-13-73
Herath, Thanuja D. K., Darveau, Richard P., Seneviratne, Chaminda J., Wang, Cun-Yu, Wang, Yu and Jin, Lijian (2013). Tetra- and Penta-Acylated Lipid A Structures of Porphyromonas gingivalis LPS Differentially Activate TLR4-Mediated NF-κB Signal Transduction Cascade and Immuno-Inflammatory Response in Human Gingival Fibroblasts. PLoS ONE, 8 (3) e58496. doi: 10.1371/journal.pone.0058496
Li, Xin, Zhu, Xiao-Fei, Zhang, Cheng-Fei, Cathro, Peter, Seneviratne, C. J. and Shen, Song (2013). Endodontic bacteria from primary and persistent endodontic lesions in Chinese patients as identified by cloning and 16S ribosomal DNA gene sequencing. Chinese Medical Journal, 126 (4), 634-639. doi: 10.3760/cma.j.issn.0366-6999.20122285
Seneviratne, C. Jayampath, Wang, Yu, Jin, Lijian, Wong, Sarah S. W., Herath, Thanuja D. K. and Samaranayake, Lakshman P. (2012). Unraveling the resistance of microbial biofilms: Has proteomics been helpful?. Proteomics, 12 (4-5), 651-665. doi: 10.1002/pmic.201100356
Da Silva, Wander Jose, Goncalves, Letícia Machado, Seneviratne, Jayampath, Parahitiyawa, Nipuna, Samaranayake, Lakshman Perera and Del Bel Cury, Altair Antoninha (2012). Exopolysaccharide matrix of developed Candida albicans biofilms after exposure to antifungal agents. Brazilian Dental Journal, 23 (6), 716-722. doi: 10.1590/S0103-64402012000600016
Chu, Chun Hung, Mei, Lei, Seneviratne, Chaminda Jayampath and Lo, Edward Chin Man (2012). Effects of silver diamine fluoride on dentine carious lesions induced by Streptococcus mutans and Actinomyces naeslundii biofilms. International Journal of Paediatric Dentistry, 22 (1), 2-10. doi: 10.1111/j.1365-263X.2011.01149.x
Leung, C. Y., Chan, Y. C., Samaranayake, L. P. and Seneviratne, C. J. (2012). Biocide resistance of Candida and Escherichia coli biofilms is associated with higher antioxidative capacities. Journal of Hospital Infection, 81 (2), 79-86. doi: 10.1016/j.jhin.2011.09.014
Gao, Xiao-Li, Seneviratne, Chaminda J., Lo, Edward C. M., Chu, Chun Hung and Samaranayake, Lakshman P. (2012). Novel and conventional assays in determining abundance of Streptococcus mutans in saliva. International Journal of Paediatric Dentistry, 22 (5), 363-368. doi: 10.1111/j.1365-263X.2011.01207.x
Watamoto, T., Samaranayake, L. P., Egusa, H., Yatani, H. and Seneviratne, C. J. (2011). Transcriptional regulation of drug-resistance genes in Candida albicans biofilms in response to antifungals. Journal of Medical Microbiology, 60 (9), 1241-1247. doi: 10.1099/jmm.0.030692-0
Seneviratne, C. J., Wong, S. S. W., Yuen, K. Y., Meurman, J. H., Parnanen, P., Vaara, M. and Samaranayake, L. P. (2011). Antifungal Susceptibility and Virulence Attributes of Bloodstream Isolates of Candida from Hong Kong and Finland. Mycopathologia, 172 (5), 389-395. doi: 10.1007/s11046-011-9444-4
Chen, Yong, Wong, Ricky W. K., Seneviratne, C. J., Hagg, Urban, Mcgrath, Colman, Samaranayake, L. P. and Kao, Richard (2011). The antimicrobial efficacy of Fructus mume extract on orthodontic bracket: a monospecies-biofilm model study in vitro. Archives of Oral Biology, 56 (1), 16-21. doi: 10.1016/j.archoralbio.2010.08.006
Seneviratne, C. J., Zhang, C. F. and Samaranayake, L. P. (2011). Dental plaque biofilm in oral health and disease. The Chinese Journal of Dental Research, 14 (2), 87-94.
Chen, Yong, Wong, Ricky W. K., Seneviratne, C. Jayampath, Hagg, Urban, McGrath, Colman and Samaranayake, Lakshman P. (2011). Comparison of the antimicrobial activity of Listerine and Corsodyl on orthodontic brackets in vitro. American Journal of Orthodontics and Dentofacial Orthopedics, 140 (4), 537-542. doi: 10.1016/j.ajodo.2011.01.022
Low, Bernard, Lee, Wilson, Seneviratne, C. J., Samaranayake, Lakshman P. and Hagg, Urban (2011). Ultrastructure and morphology of biofilms on thermoplastic orthodontic appliances in 'fast' and 'slow' plaque formers. European Journal of Orthodontics, 33 (5), 577-583. doi: 10.1093/ejo/cjq126
Wong, R. W.K., Hägg, U., Samaranayake, L., Yuen, M. K.Z., Seneviratne, C. J. and Kao, R. (2010). Antimicrobial activity of Chinese medicine herbs against common bacteria in oral biofilm. A pilot study. International Journal of Oral and Maxillofacial Surgery, 39 (6), 599-605. doi: 10.1016/j.ijom.2010.02.024
So, Cheung-Wai, Tsang, Paul W. K., Lo, Pui-Chi, Seneviratne, C. J., Samaranayake, Lakshman P. and Fong, Wing-Ping (2010). Photodynamic inactivation of Candida albicans by BAM-SiPc. Mycoses, 53 (3), 215-220. doi: 10.1111/j.1439-0507.2008.01688.x
Watamoto, T., Samaranayake, L. P., Egusa, H., Yatani, H., Samaranayake, Y. H. and Seneviratne, C. J. (2010). Susceptibility of Candida albicans filamentation-defective mutants to clinical biocides. Journal of Hospital Infection, 74 (2), 189-191. doi: 10.1016/j.jhin.2009.10.017
Da Silva, Wander Jose, Seneviratne, Jayampath, Samaranayake, Lakshman Perera and Del Bel Cury, Altair Antoninha (2010). Bioactivity and architecture of Candida albicans biofilms developed on poly(methyl methacrylate) resin surface. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 94 (1), 149-156. doi: 10.1002/jbm.b.31635
Seneviratne, C. Jayampath, Zhang, T., Fang, H. H. P., Jin, L. J. and Samaranayake, L. P. (2009). Distribution coefficients of dietary sugars in artificial Candida biofilms. Mycopathologia, 167 (6), 325-331. doi: 10.1007/s11046-009-9184-x
Seneviratne, C. J., Silva, W. J., Jin, L. J., Samaranayake, Y. H. and Samaranayake, L. P. (2009). Architectural analysis, viability assessment and growth kinetics of Candida albicans and Candida glabrata biofilms. Archives of Oral Biology, 54 (11), 1052-1060. doi: 10.1016/j.archoralbio.2009.08.002
Thein, Z. M., Seneviratne, C. J., Samaranayake, Y. H. and Samaranayake, L. P. (2009). Community lifestyle of Candida in mixed biofilms: a mini review. Mycoses, 52 (6), 467-475. doi: 10.1111/j.1439-0507.2009.01719.x
Watamoto, T., Samaranayake, L. P., Jayatilake, J. A. M. S., Egusa, H., Yatani, H. and Seneviratne, C. J. (2009). Effect of filamentation and mode of growth on antifungal susceptibility of Candida albicans. International Journal of Antimicrobial Agents, 34 (4), 333-339. doi: 10.1016/j.ijantimicag.2009.03.008
Samaranayake, Y. H., Cheung, B. P. K., Parahitiyawa, N., Seneviratne, C. J., Yau, J. Y. Y., Yeung, K. W. S. and Samaranayake, L. P. (2009). Synergistic activity of lysozyme and antifungal agents against Candida albicans biofilms on denture acrylic surfaces. Archives of Oral Biology, 54 (2), 115-126. doi: 10.1016/j.archoralbio.2008.09.015
Wang, Yu and Seneviratne, Jayampath (2008). Biomarker discovery in clinical proteomics: Strategies for exposing low abundant proteins. Current Proteomics, 5 (2), 104-114. doi: 10.2174/157016408784911927
Seneviratne, C. J., Jin, L. and Samaranayake, L. P. (2008). Biofilm lifestyle of Candida: a mini review. Oral Diseases, 14 (7), 582-590. doi: 10.1111/j.1601-0825.2007.01424.x
Seneviratne, C. J. and Samaranayake, L. P. (2008). An overview of H5n1 infection and its implications for dentistry. International Journal of Clinical Dentistry, 1 (1), 27-44.
da Silva, Wander José, Seneviratne, Jayampath, Parahitiyawa, Nipuna, Rosa, Edvaldo Antonio Ribeiro, Samaranayake, Lakshman Perera and del Bel Cury, Altair Antoninha (2008). Improvement of XTT assay performance for studies involving Candida albicans biofilms. Brazilian Dental Journal, 19 (4), 364-369. doi: 10.1590/s0103-64402008000400014
Seneviratne, C. Jayampath, Wong, Ricky W. K. and Samaranayake, Lakshman P. (2008). Potent anti-microbial activity of traditional Chinese medicine herbs against Candida species. Mycoses, 51 (1), 30-34. doi: 10.1111/j.1439-0507.2007.01431.x
Seneviratne, C. J., Jin, L. J., Samaranayake, Y. H. and Samaranayake, L. P. (2008). Cell density and cell aging as factors modulating antifungal resistance of Candida albicans biofilms. Antimicrobial Agents and Chemotherapy, 52 (9), 3259-3266. doi: 10.1128/AAC.00541-08
Seneviratne, C. Jayampath, Wang, Yu, Jin, Lijian, Abiko, Yoshi and Samaranayake, Lakshman P. (2008). Candida albicans biofilm formation is associated with increased anti-oxidative capacities. Proteomics, 8 (14), 2936-2947. doi: 10.1002/pmic.200701097
Conference Papers
Rosa, V., Vidhawan, A. S., Seneviratne, C. J. and Silikas, N. (2023). Graphene nanocoating inhibits cross-kingdom biofilms on titanium. Academy of Dental Materials Annual Meeting, Athens, Greece, 2022. ph: Elsevier. doi: 10.1016/j.dental.2023.08.124
Chee, H.K., Htoon, H.M. and Seneviratne, C.J. (2023). IDF2022-0987 Development of a Clinical Risk Model for Targeted Screening of Undiagnosed Diabetes in Asian Dental Settings. IDF World Diabetes Congress 2022, Lisbon, Portugal, 5-8 December 2022. Shannon, Ireland: Elsevier Ireland. doi: 10.1016/j.diabres.2023.110493
Thesis
Athukorala Arachchi Seneviratne, Chaminda Jayampath (2008). Molecular microbiology of candida biofilms. PhD Thesis, School of Dentistry, The University of Hong Kong. doi: 10.5353/th_b4068751